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IDENTIFICATION AND ANALYSIS OF REGULATORY AND SEXUAL STAGE GENES IN THE GENOMES OF BABESIA AND THEILERIA PARASITES
(2016)
The tick borne apicomplexan parasites Babesia and Theileria are responsible for costly and devastating diseases globally. Improved control is needed but the biology of these parasites remains poorly understood. Significant ...
To Be, or Not to Be: The Molecular Mechanisms that Regulate Spermatogonial Stem Cell Fate
(2015)
Spermatogonial stem cells (SSCs) are a rare population of cells in the male germ line that self-renew and differentiate into progenitor spermatogonia for the initiation of spermatogenesis. In mammalian males, this process ...
RETINOIC ACID SYNTHESIS AND DEGRADATION: IMPLICATIONS FOR PROPER GERM CELL DEVELOPMENT
(2015)
Spermatogenesis is absolutely essential for mammalian reproduction. This highly organized and tightly controlled process is regulated, in part, by retinoic acid (RA). This essential molecule plays key roles in many aspects ...
SLEEP DISTURBANCES AFTER CHRONIC ALCOHOL CONSUMPTION: HOMEOSTATIC DYSREGULATION OR CIRCADIAN DESYNCHRONY?
(2016)
Chronic alcohol use often leads to sleep disturbances such as insomnia and sleep fragmen¬ta¬¬tion, but the underlying mecha¬nisms are not fully understood. Sleep is regulated by two main processes: a homeo¬static process ...
CHARACTERIZATION OF A GREEN FLUORESCENT PROTEIN EXPRESSING
(2013)
Anaplasma marginale is a tick-transmitted, obligate intraerythrocytic pathogen of cattle, causing anaplasmosis characterized by anemia, decreased milk and meat production, and occasionally death. Animals that survive are ...
ELUCIDATING MECHANISMS FOR PERSISTENT INFECTION BY THE RELAPSING FEVER SPIROCHETE BORRELIA HERMSII
(2016)
Relapsing fever is a tick-borne bacterial disease caused by a number of species in the genus Borrelia. Persistence is a key component of the lifecycle of relapsing fever Borrelia as it improves the chance for tick acquisition ...
TRANSCRIPTOME ANALYSIS OF VIBRIO PARAHAEMOLYTICUS IN TYPE III SECRETION SYSTEM 1 INDUCING CONDITIONS
(2014)
Vibrio parahaemolyticus is a bacterial pathogen capable of causing gastroenteritis, wound infections and septicemia. Its virulence factors include two type III secretion systems (T3SS1 and T3SS2) that cause host-cell ...