• EFFECTS OF MYOSIN HEAVY CHAIN ISOFORMS AND CARDIOMYOPATHY MUTATIONS ON SARCOMERE LENGTH-DEPENDENT ACTIVATION 

  Reda, Sherif (2019)

  Heritable mutations in cardiac muscle proteins lead to hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. There is a lack of knowledge on how HCM/DCM-related mutations alter the molecular ...

• Identifying intracellular roles of the Salmonella invasion-associated injectisome 

  Klein, Jessica Abbey (2018)

  Intracellular pathogens either reside within host-derived vacuoles or escape this compartment to inhabit the cytosol. Why some bacteria lyse their internalization vacuole and others cannot remains enigmatic in Gram-negative ...

• ENVIRONMENTAL EFFECTS ON SPERMATOGENESIS 

  Horan, Tegan (2018)

  Compelling evidence from human populations worldwide suggest that sperm counts have declined by ~50% over the last 40 years. It is thought perinatal exposure to endocrine disrupting chemicals (EDCs), such as bisphenol A ...

• REGULATION, FUNCTION AND POTENTIAL APPLICATIONS OF MICROCIN PDI FOR MEDICINE AND FOOD SAFTEY 

  Lu, Shao Yeh (2018)

  Microcin PDI (mccPDI) is a class IIa microcin that is encoded as a five-locus genetic unit that is borne by a conjugative plasmid. The microcin was first discovered in Escherichia coli strains 25 and 264 (cattle origin) ...

• BABESIA BIGEMINA TICK STAGE SPECIFIC GENES DURING PARASITE DEVELOPMENT WITHIN ADULT FEMALE RHIPICEPHALUS MICROPLUS 

  Bohaliga, Gamila (2018)

  Babesia bigemina is an intra-erythrocytic parasite that infect cattle and transmitted by tick vectors transovarian transmission. This parasite causes bovine babesiosis (tick cattle fever) and has enormous veterinary, ...

• ENHANCING SPERM PRODUCTION IN THE BULL 

  Waqas, Muhammad Salman (2018)

  Spermatogenesis is a complex process highly regulated mainly by somatic cells of testes, the Sertoli cells. The number of Sertoli cells for a male is fixed between birth and puberty, and does not increase after puberty ...

• Disentangling the wicked problem of antibiotic resistance 

  Omulo, Sylvia Adhiambo (2017)

  Antimicrobial resistance (AMR) is currently an urgent public health concern worldwide. For low-income regions such as sub-Saharan Africa, absence of surveillance data and systematic investigations of risk factors prevents ...

• Characterization of Ovine herpesvirus 2 putative glycoprotein Ov8 

  Alhajri, Salim Mohamed (2017)

  Malignant catarrhal fever (MCF) is a lymphoproliferative usually fatal disease of ungulates caused by several gammaherpesviruses in the genus Macavirus including alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 ...

• HYPERTONIC TREATMENTS ENHANCE THE EFFICACY OF ANTIBIOTICS AGAINST BACTERIAL BIOFILM COMMUNITIES 

  Falghoush, Azeza Mohamed (2017)

  Biofilm is a structured community of bacterial cells enclosed in a self-produced matrix of extracellular polymeric substance (EPS). Biofilms have long been implicated in bacterial infections that are mostly untreatable. ...

• EFFECTS OF CARDIOMYOPATHY-RELATED MUTATIONS IN THE N-TERMINUS OF CARDIAC TROPONIN T AND IMPLICATIONS FOR CARDIAC DYSFUNCTION 

  Mickelson, Alexis (2017)

  Hypertrophic cardiomyopathy (HCM)-related mutations in the N-terminus of cardiac troponin T (TnT) are associated with cardiac dysfunction and a high incidence of sudden cardiac death, however, the primary myofilament ...

• Analysis of the anti-migraine effects of THC using home cage wheel running 

  Kandasamy, Ram (2017)

  Migraine is a common neurological disorder characterized by severe headache and depression of normal activity. Despite its marked prevalence, migraine is poorly treated and no new anti-migraine agents have emerged in over ...

• MYCOPLASMA BOVIS ASSOCIATED DISEASES: MODELING STRESS AND ITS EFFECT ON BOVINE IMMUNE FUNCTION 

  Alabdullah, Hussain Ali (2017)

  Mycoplasma bovis associated diseases are newly emerging causing significant economic losses in the cattle industry. Therefore, it is necessary to understand the pathogenesis of M. bovis to develop new preventive methods ...

• CHANNELING SATIATION AT THE ST-NTS SYNAPSE: THE ROLES OF TRP CHANNELS 

  Wu, Shaw-wen (2016)

  Vagal afferent neurons relay meal-related signals from the gut to the hindbrain nucleus of the solitary tract (NTS) providing key controls of feeding and gastrointestinal reflexes. Centrally, vagal afferents form strong ...

• IDENTIFICATION AND ANALYSIS OF REGULATORY AND SEXUAL STAGE GENES IN THE GENOMES OF BABESIA AND THEILERIA PARASITES 

  Alzan, Heba Fathy (2016)

  The tick borne apicomplexan parasites Babesia and Theileria are responsible for costly and devastating diseases globally. Improved control is needed but the biology of these parasites remains poorly understood. Significant ...

• Protective effects of an experimental sporozoite-based immunization strategy against Theileria equi 

  Ochoa, Jennine Nicole (2016)

  Theileria equi is a tick-transmitted apicomplexan hemoparasite parasite of equids with a worldwide distribution and a cause of equine piroplasmosis, a World Organization of Animal Health (OIE) reportable disease. Although ...

• SLEEP DISTURBANCES AFTER CHRONIC ALCOHOL CONSUMPTION: HOMEOSTATIC DYSREGULATION OR CIRCADIAN DESYNCHRONY? 

  Guo, Rong (2016)

  Chronic alcohol use often leads to sleep disturbances such as insomnia and sleep fragmen¬ta¬¬tion, but the underlying mecha¬nisms are not fully understood. Sleep is regulated by two main processes: a homeo¬static process ...

• The role of excreted antibiotics in the establishment of persistent on-farm reservoirs of antibiotic-resistant bacteria 

  Liu, Jinxin (2016)

  Bioavailable antibiotic residues from treated animals likely contribute to the persistence of antibiotic-resistant bacteria in agricultural systems. To determine the magnitude of this effect, we evaluated changes in the ...

• COMPARATIVE INVESTIGATION OF THE IMMUNE SYSTEMS OF TWO OVINE SPECIES (OVIS ARIES AND OVIS CANADENSIS) 

  Highland, Margaret Ann (2016)

  Chapter 1 describes the economic and ecologic significance of respiratory disease in domestic sheep (DS; Ovis aries) and bighorn sheep (BHS; Ovis canadensis) and the need for interspecies comparative immune analyses. In ...

• ELUCIDATING MECHANISMS FOR PERSISTENT INFECTION BY THE RELAPSING FEVER SPIROCHETE BORRELIA HERMSII 

  James, Allison Eavey (2016)

  Relapsing fever is a tick-borne bacterial disease caused by a number of species in the genus Borrelia. Persistence is a key component of the lifecycle of relapsing fever Borrelia as it improves the chance for tick acquisition ...

• THEILERIA PARVA: IMMUNOPATHOLOGY, CORRELATES OF PROTECTION, AND VACCINE DEVELOPMENT 

  Fry, Lindsay Michelle (2016)

  East Coast Fever (ECF), caused by the apicomplexan parasite, Theileria parva, kills over a million cattle each year in sub-Saharan Africa. Cattle that develop ECF succumb to respiratory failure-induced pulmonary edema; ...

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