Browsing Electronic Dissertations and Theses - Veterinary Medicine by Title
Now showing items 68-79 of 79
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THE DYNAMIC INTERACTION BETWEEN CIRCADIAN RHYTHMS AND DRUG-TAKING: EVIDENCE FROM BEHAVIOR ANALYSES IN RATS
(2012)Extensive research links circadian rhythms and drug addiction. In this thesis I examined the interaction between circadian rhythms and drug-taking. In my first experiment, I studied the effect of free-running (non-entrained) ... -
THE MOLECULAR MECHANISMS OF TICK PATHOGEN TRANSMISSION
(2016)Ticks vector numerous diseases important to livestock and humans and are often indispensable to the life cycle and continued existence of these agents. However, little is known about their biology and interactions with the ... -
The role of cardiac troponin T-troponin I interactions in regulating cardiac function in health and disease
(2012)Alterations of cardiac contractile proteins are a known cause or consequence of heart disease; however, little is known about how particular alterations in cardiac contractile proteins affect contractile function. ... -
The role of excreted antibiotics in the establishment of persistent on-farm reservoirs of antibiotic-resistant bacteria
(2016)Bioavailable antibiotic residues from treated animals likely contribute to the persistence of antibiotic-resistant bacteria in agricultural systems. To determine the magnitude of this effect, we evaluated changes in the ... -
THE ROLE OF LIPID ANTIGENS IN THE PROTECTION AGAINST RHODOCOCCAL PNEUMONIA
(2014)Rhodococcus equi is an actinomycete bacterium that is closely to Mycobacterium tuberculosis. It is also an important cause of pneumonia in young horses worldwide. Like M. tuberculosis, R. equi persists within macrophages ... -
The Role of the Nipah Virus G Head and Stalk Regions in Modulating Viral Fusion
(2015)Nipah virus (NiV) is an emerging zoonotic virus within the paramyxovirus family that causes severe neurological and respiratory disease in its victims and has mortality rates in humans of up to one hundred percent. Membrane ... -
THEILERIA PARVA: IMMUNOPATHOLOGY, CORRELATES OF PROTECTION, AND VACCINE DEVELOPMENT
(2016)East Coast Fever (ECF), caused by the apicomplexan parasite, Theileria parva, kills over a million cattle each year in sub-Saharan Africa. Cattle that develop ECF succumb to respiratory failure-induced pulmonary edema; ... -
To Be, or Not to Be: The Molecular Mechanisms that Regulate Spermatogonial Stem Cell Fate
(2015)Spermatogonial stem cells (SSCs) are a rare population of cells in the male germ line that self-renew and differentiate into progenitor spermatogonia for the initiation of spermatogenesis. In mammalian males, this process ... -
TRANSCRIPTOME ANALYSIS OF VIBRIO PARAHAEMOLYTICUS IN TYPE III SECRETION SYSTEM 1 INDUCING CONDITIONS
(2014)Vibrio parahaemolyticus is a bacterial pathogen capable of causing gastroenteritis, wound infections and septicemia. Its virulence factors include two type III secretion systems (T3SS1 and T3SS2) that cause host-cell ... -
UNCOVERING A REGION IN THE NIPAH VIRUS ATTACHMENT PROTEIN IMPORTANT FOR TRIGGERING MEMBRANE FUSION
(2014)Membrane fusion is essential for entry of the biomedically-important Nipah virus (NiV) into their host cells (viral-cell fusion), and for syncytia formation (cell-cell fusion), often induced by NiV infections. For NiV, ... -
UNDERSTANDING GERM CELL REGULATION USING BIOINFORMATIC APPROACHES
(2015)Bioinformatics is a powerful tool which has been utilized to study diseases (i.e cancer) and complex biological systems including the immune system, neural interactions in the brain and testis biology. Only recently has ... -
Vaccination of cattle with Escherichia coli O157:H7-derived proteins results in humoral and cellular immune responses but does not confer protection against subsequent challenge
(2013)Escherichia coli O157:H7 is an enteric pathogen of animals and humans that colonizes the gastrointestinal tract and can result in deadly sequelae. Cattle are most frequently colonized at the recto-anal junction and are ...