Now showing items 1-10 of 19
Understanding the Physiological Significance of Ureide Transport Processes in Soybean (
The ureides allantoin and allantoic acid are the major long-distance forms of nitrogen (N) in nodulated tropical legumes like French bean (
CHARACTERIZATION OF MITOCHONDRIAL AND CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASES
As a folate-dependent enzyme, serine hydroxymethyltransferase (SHMT) catalyzes the reversible conversion of L-serine and (6S)-H4PteGlun (tetrahydrofolate, THF) to glycine and (6S)-5,10-CH2-H4PteGlun. The glycine-forming ...
JASMONATE BIOSYNTHESIS AND SIGNALING IN THE BALANCE OF PLANT GROWTH AND DEFENSE
Jasmonic acid (JA) is a plant hormone that controls many aspects of growth, development, and defense. As a defense hormone JA is rapidly synthesized in response to wounding, or attack from herbivores and pathogens, triggering ...
Optimizing the Enzyme/Prodrug Axis of Suicide Gene Therapy Using Protein Engineering Strategies
The unifying goal of cancer therapy is to selectively eradicate cancer cells while sparing normal tissue from damage. As many current anticancer therapies lack specificity and cause unwanted side effects there is an unmet ...
Characterization of Cobalamin-Dependent Radical S-Adenosyl-L-Methionine Methyltransferases Involved in Antibiotic Biosynthesis
Due to increasing antibiotic resistance among dangerous pathogens, there is a critical need for new antibiotics. Enzymes represent a powerful tool for antibiotic production and discovery, however more enzymatic mechanisms ...
Arabidopsis Arogenate Dehydratases: Influence on Aromatic Amino Acid and Downstream Phenylpropanoid Biosynthesis
Arogenate dehydratases (ADTs) perform the final step of phenylalanine (Phe) biosynthesis in plants. As one of twenty protein-coding amino acids, Phe is essential in all living organisms, and in plants it is also a precursor ...
Genetic Pathways Involved in Omega-6 Fatty Acid-Induced Sterility in C. elegans
Polyunsaturated fatty acids serve both structural and functional roles as membrane components as well as precursors for a number of different factors involved in inflammation and signaling. Humans are unable to synthesize ...
Development and Application of Spectral Databases and Mathematical Models in the Study of Plant Natural Products Biosynthesis
Plant natural products are useful for many different applications, including medicines, flavors and fragrances, and industrial uses. Two important aspects of plant natural products research are the identification of compounds ...
TEMPLATE INDEPENDENT DOUBLE STRAND BREAK REPAIR AND RECOMBINASE MODULATION IN THE ARCHAEON SULFOLOBUS SOLFATARICUS
The repair of double strand breaks (DSB) is a fundamental process that plays a key role in cell survival and evolution. DSB repair is required for cell survival, and a variety of pathways have evolved. Homologous ...