Antibiotic-Associated Diarrhea (AAD) is a serious complication of antimicrobial therapy. There is emerging interest in the health benefits of probiotics for a plethora of illnesses. Studies have demonstrated the efficacy of probiotics for respiratory infections, dental caries, irritable bowel syndrome and inflammatory bowel disease. Probiotics may also have a role in the prevention of
AAD. From 1994 to 2003 U.S. citizens nearly tripled the amount spent on probiotic purchases. Probiotics are considered a natural and safe remedy by many. It is the nurse practitioner's responsibility to advise and educate patients with the latest evidence-based information regarding the role of probiotic therapy in the prevention of AAD.