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Identification of novel differentially methylated dna regions using active learning and imbalanced class learners
Epigenetics refers to the changes in gene expression which are caused by other mechanisms other than the DNA sequence. Environmental influences can alter epigenetic states in the germ line that can be further transmitted ...
Computational approaches for the prediction of apicoplast-targeted proteins
Motivation:The cells of eukaryotic organisms contain subunits called organelles. The apicoplast is a unique organelle found in a group of parasites, known as Apicomplexa, that are responsible for a wide range of serious ...
SCALABLE PARALLEL METHODS FOR ANALYZING METAGENOMICS DATA AT EXTREME SCALE
The field of bioinformatics and computational biology is currently experiencing a data revolution. The exciting prospect of making fundamental biological discoveries is fueling the rapid development and deployment of ...
Computational methods for estimating genetic relationships
The advent of molecular methods has altered our approach to the studyof the genetic relationships of microbes. In particular, we now havethe unprecedented ability to estimate genetic relationships from wholegenome sequences ...