Now showing items 1-6 of 6
IDENTIFICATION AND ANALYSIS OF REGULATORY AND SEXUAL STAGE GENES IN THE GENOMES OF BABESIA AND THEILERIA PARASITES
The tick borne apicomplexan parasites Babesia and Theileria are responsible for costly and devastating diseases globally. Improved control is needed but the biology of these parasites remains poorly understood. Significant ...
SLEEP DISTURBANCES AFTER CHRONIC ALCOHOL CONSUMPTION: HOMEOSTATIC DYSREGULATION OR CIRCADIAN DESYNCHRONY?
Chronic alcohol use often leads to sleep disturbances such as insomnia and sleep fragmen¬ta¬¬tion, but the underlying mecha¬nisms are not fully understood. Sleep is regulated by two main processes: a homeo¬static process ...
Understanding the Molecular Link Between FSH and IGF-1 Signaling in Rat Granulosa Cells
Mouse knockout models define follicle-stimulating hormone (FSH) and insulin-like growth factor-1 (IGF-1) as pivotal co-regulators of ovarian follicle maturation and hence, female fertility. Moreover, numerous studies report ...
ELUCIDATING MECHANISMS FOR PERSISTENT INFECTION BY THE RELAPSING FEVER SPIROCHETE BORRELIA HERMSII
Relapsing fever is a tick-borne bacterial disease caused by a number of species in the genus Borrelia. Persistence is a key component of the lifecycle of relapsing fever Borrelia as it improves the chance for tick acquisition ...
YB1: A New Player in FSH Regulation of Gene Expression in Granulosa Cells
Within the ovarian follicle, immature oocytes are surrounded and supported by granulosa cells (GCs). Stimulation of GCs by follicle stimulating hormone (FSH) promotes their proliferation and differentiation, events that ...
THE MOLECULAR MECHANISMS OF TICK PATHOGEN TRANSMISSION
Ticks vector numerous diseases important to livestock and humans and are often indispensable to the life cycle and continued existence of these agents. However, little is known about their biology and interactions with the ...