Browsing Monroe, Cara by Issue Date
Now showing items 1-4 of 4
To clone or not to clone: Method analysis for retrieving consensus sequences in ancient DNA samples (Public Library of Science, 2011)The challenges associated with the retrieval and authentication of ancient DNA (aDNA) evidence are principally due to postmortem damage which makes ancient samples particularly prone to contamination from ‘‘modern’’ DNA ...
How Much DNA is Lost? Measuring DNA Loss of Short-Tandem-Repeat Length Fragments Targeted by the PowerPlex 16? System Using the Qiagen MinElute Purification Kit (Human Biology, 2014)The success in recovering genetic profiles from aged and degraded biological samples is diminished by fundamental aspects of DNA extraction, as well as its long-term preservation, that are not well understood. While numerous ...
Detection of Cytosine Methylation in Ancient DNA from Five Native American Populations Using Bisulfite Sequencing (Public Library of Science, 2015)While cytosine methylation has been widely studied in extant populations, relatively few studies have analyzed methylation in ancient DNA. Most existing studies of epigenetic marks in ancient DNA have inferred patterns of ...