Now showing items 1-4 of 4
Using protein clusters from whole proteomes to construct and augment a dendrogram
(Advances in Bioinformatics, 2013-01)
In this paper we present a new ab initio approach for constructing an unrooted dendrogram using protein clusters, an approach that has the potential for estimating relationships among several thousands of species based on ...
Whole-proteome analysis of twelve species of Alphaproteobacteria links four pathogens
Thousands of whole-genome and whole-proteome sequences have been made available through advances in sequencing technology, and sequences of millions more organisms will become available in the coming years. This wealth of ...
Genetic relationships among 527 Gram-negative bacterial plasmids
Plasmids are mosaic in composition with a maintenance “backbone” as well as “accessory” genes obtained via horizontal gene transfer. This horizontal gene transfer complicates the study of their genetic relationships. We ...
Computational methods for estimating genetic relationships
The advent of molecular methods has altered our approach to the studyof the genetic relationships of microbes. In particular, we now havethe unprecedented ability to estimate genetic relationships from wholegenome sequences ...