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    Johnson, Adam J. (1)
    Subject5-fluorocytosine (1)Biochemistry (1)cytosine deaminase (1)deoxycytidine kinase (1)deoxyguanosine kinase (1)enzyme engineering (1)Molecular biology (1)Oncology (1)suicide gene therapy (1)... View MoreDate Issued2011 (1)

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    Optimizing the Enzyme/Prodrug Axis of Suicide Gene Therapy Using Protein Engineering Strategies 

    Johnson, Adam J. (2011)
    The unifying goal of cancer therapy is to selectively eradicate cancer cells while sparing normal tissue from damage. As many current anticancer therapies lack specificity and cause unwanted side effects there is an unmet ...